Kim Morin, Technical Support Specialist, has the answers. In this practical video, Dilutions and Admixtures using VALIDATE® Products, she covers:
If your facility decides that the VALIDATE® Level 1 value isn’t close enough to the lower AMR for an analyte, a dilution using Level 1 and manufacturer-recommended diluent can be performed. These dilutions can also be used if you want to extend the AMR beyond the manufacturer’s stated range.
In cases where a facility determines that VALIDATE® Level 5 value isn’t close enough to the higher AMR, or to extend the AMR beyond manufacturer’s stated range, an admixture using Level 5 and a high sample can be performed to recover a higher level.
While we recognize these higher recovery admixtures are possible to perform, we don’t recommend them since they may not recover a linear response.
In addition to providing more detailed information about the process, in the dilution video, Kim reviews:
Once your dilution form is submitted, our Technical Support Staff uses the information you provide to calculate the effective X for the new level created.
LGC Clinical Diagnostics Technical Support can help! They’re available to provide recommendations with general recovered values based on theoretical calculations.
For the best recommendations, it’s important to provide mean recovered values of VALIDATE® Level 1 and 3 (if 1 is recovering non-numerical values, use 2 and 3) and the range of recovered values being targeted.
Call 1-800-377-9684 or email MSC.techsupport@LGCGroup.com for your dilution recommendation.